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The Breast Cancer Now Generations Study team at The Institute of Cancer Research, London.
Improved breast cancer risk tools on the horizon as major study reaches 20-year halfway point

16/09/24

Scientists are developing breast cancer risk tools that will help to identify women at high risk, even if they do not have a family history of the disease, thanks to one of the world’s largest and longest-running studies into the causes of breast cancer.
An MRI scanner at the Royal Marsden Hospital
New method could lower radiotherapy doses for some cancer patients

14/08/24

A special type of MRI scan where patients inhale 100% oxygen could result in lower radiotherapy doses for some cancer patients.
white blood cell
Scientists uncover promising new treatment strategy for aggressive form of leukaemia

18/04/24

Scientists have uncovered a promising treatment strategy for an aggressive type of leukaemia – through targeting the enzymes that cells normally use to sense and adapt to changing oxygen levels.
ICR Logo
Scientists discover how some advanced breast cancers become resistant to hormone therapy

07/02/24

New research has identified why some advanced oestrogen receptor (ER) positive breast cancers become resistant to hormone therapy, and has identified drugs currently in development that could keep disease stable for longer for these patients.
Prostate Cancer Cells 547x411px
Scientists now able to predict response to radium-223 treatment in prostate cancer bone metastases

21/12/23

Researchers have found a way to predict which patients are likely to respond to radium-223, a standard treatment for advanced prostate cancer that has spread to the bones.
Immunofluorescent image of autophagosomes in multiple myeloma cells 547x410px
Next-generation trial shows five-drug combo can keep ‘ultra-high-risk’ bone marrow cancer at bay

23/06/23

Combining five existing drugs can keep a highly aggressive type of bone marrow cancer at bay for longer, an innovative trial has shown.
Centre for Cancer Drug Discovery
ICR-discovered drug to enter phase II clinical trial in ovarian cancer thanks to new research collaboration

04/05/23

An innovative cancer drug discovered by scientists at The Institute of Cancer Research, London, is set to enter a new clinical trial.
Clinical trials pharmacy (Jan Chlebik for the ICR, 2014)
Innovative first in class HSF1 pathway cancer drug shows strong results in new study

05/04/23

A new, oral ‘first in class’ experimental cancer drug has shown potent activity against cancer cells and caused shrinkage of hard-to-treat human ovarian tumours grown in mice, a new study shows.
Myeloma cells producing monoclonal proteins of varying types
Genetic test can guide treatment for blood cancer to help prevent relapse

19/03/23

Scientists have found a new way to predict which patients with the blood cancer myeloma will benefit the most from a treatment often used to help keep the disease from coming back after a bone marrow transplant.
Structural map including the 'Cullin 2 RING' E3 ligase. From Faull S et al (2019). Nat Comms 10:3814.
‘Molecular glue degrader’ reaches cancer trial following ICR research programme

23/02/23

The biotechnology company Monte Rosa Therapeutics – originally a spin-out from research at The Institute of Cancer Research, London – has announced that the first patient has received their ‘molecular glue degrader’ drug as part of a clinical trial in oncology.
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Study opens route to overcoming drug resistance in stomach cancer

23/10/22

Scientists have shown how stomach cancers can dodge the effects of a promising new experimental treatment – raising the possibility of outsmarting cancer by predicting drug resistance in advance.
Person filling a syringe with Covid-19 vaccine
First Covid jab provides protection for most myeloma blood cancer patients

19/04/21

A single dose of a Covid-19 vaccine triggers an immune response in around 70 per cent of patients with myeloma – suggesting that it does provide protection against the virus.