Cancer discovery news

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3d reconstruction of the human breast
New data tool could bring RNA sequencing into standard clinical practice, improving diagnosis and treatment

06/02/25

Researchers have developed a new tool that could help clinicians diagnose the most common type of breast cancer more accurately and make better treatment decisions.
Breast cancer cells Credit Ewa Krawczyk 945x532
Breast cancer risk model provides reassuring data for those with family history of disease after short-term HRT use

31/01/25

Hormone replacement therapy taken at age 50 for up to 5 years only modestly increases the risk of breast cancer, even for women with a strong family history of the disease, according to a new risk model published in the British Journal of General Practice.
Mini tumours grown from a bowel cancer
Scientists create new way to predict bowel cancer risk in people with inflammatory bowel disease

30/01/25

Scientists at The Institute of Cancer Research, London, have found a way to identify people with inflammatory bowel disease (IBD) who are at the highest risk of developing bowel cancer.
Image: Blood samples. Credit: Ahmad Ardity via Pixabay
Genetic testing for Lynch Syndrome prevents cancers being missed

17/01/25

Genetic testing to identify women with Lynch Syndrome is likely to need to increase dramatically to ensure that carriers are not missed, a new analysis by ICR researchers has found.
Image of immunofluorescence staining of bladder tumour tissue. Some areas appear lighter green, some dark blue, and others black.
MRI scanning and biopsy could reduce delays in the correct treatment for bladder cancer by more than six weeks

16/01/25

Patients with a common aggressive type of bladder cancer could get correct treatment significantly quicker as new research suggests that initial MRI imaging and biopsy could be used to reduce the time patients wait.
Red, yellow and blue microscope image of immunofluorescence staining showing extension of prostatic adenocarcinoma into the bladder wall
New drug hope for prostate cancer patients

10/01/25

Prostate cancer that has become resistant to hormone therapy could be treated using a new drug that is currently in clinical trials for ovarian and bile duct cancer, according to research published in the journal Clinical Cancer Research.
breast cancer cell
Major trial shows prolonged benefit of olaparib in early-stage inherited breast cancer

12/12/24

One year of treatment with the targeted drug olaparib improves long-term survival in women with high-risk, early-stage breast cancer with mutations in BRCA1 or BRCA2 genes, new results from a major clinical trial show.
Breast cancer cell spheroid blue and purple
New understanding of aggressive form of breast cancer paves the way for tests and treatments

10/12/24

Scientists have developed a machine learning tool that can predict how an aggressive type of breast cancer will respond to treatment, and when it will return.
Johann de Bono and Mateus Crespo Prostate cancer cells 547x410
Scientists can predict how long prostate cancer patients will respond to olaparib

21/11/24

Scientists have worked out a way of predicting how long a prostate cancer patient will continue to respond to the PARP inhibitor drug, olaparib, according to new research published in the journal Cancer Cell.
NovaSeq genome sequencing machine
New potential cancer-driving genes unveiled, opening new paths for precision treatments

19/11/24

Researchers have carried out an in-depth analysis of 10,478 cancer genomes across 35 different cancer types, identifying 330 potential cancer-driving genes, 74 of which are newly associated with cancer. The findings highlight the potential to develop new, more targeted treatment options for cancer patients.
New treatment target for aggressive leukaemia discovered by disrupting its genome organisation

12/11/24

Researchers have identified a key weakness in acute myeloid leukaemia, offering a promising new strategy to delay the progression of this aggressive blood cancer. The discovery focuses on disrupting the function of a certain protein complex that cancer cells, including leukaemia cells, rely on to maintain their abnormal growth.
Metastatic breast cancer cells in pleural fluid
Powerful new therapy doubles progression-free survival in advanced breast cancer

30/10/24

A three-drug combination for aggressive advanced breast cancer doubles the length of time before the cancer progresses, compared with a drug combination currently available on the NHS, new research has shown.