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Resistance-busting ICR drug enters clinical trial
A drug discovered at The Institute of Cancer Research that could counteract drug resistance in patients with cancers including acute myeloid leukaemia has entered a phase I clinical trial at The Royal Marsden NHS Foundation Trust.
Researchers reveal discovery of new cancer drug fadraciclib
Scientists have revealed details of the discovery of a new cancer drug that could be used to treat a range of cancer types, including some blood cancers and solid tumours.
Drug used in breast and ovarian cancer could lead to safer, more effective treatment for neuroblastoma
A type of drug known as a PARP inhibitor, already used to treat breast and ovarian cancer, may be useful in treating children with high-risk neuroblastoma – a common childhood tumour with a low survival rate.
Three-minute MRI scan could safely and effectively test new precision treatments for children with neuroblastoma
A simple non-invasive MRI scan could play a key role in guiding the delivery of precision medicine to children with neuroblastoma – reducing the need for surgery, a new study has found.
Immunotherapy could work against bowel cancers resistant to important targeted treatment
Patients with bowel cancer who have stopped responding to a widely used targeted drug could benefit from immunotherapy, a major new study reveals.
ASCO 2019: ICR-discovered drug shows promise in phase I clinical trial
A precision medicine targeting a key protein which helps cancer cells to tolerate DNA damage has shown promising results in two clinical trials.
Gene test predicts likelihood of stomach or oesophageal cancer relapse
A new test could improve care for patients with stomach or oesophageal cancer by predicting their likelihood of relapse after chemotherapy and surgery.
Immunotherapy drug for skin disease could boost hormone treatment for prostate cancer
A new form of immunotherapy reactivates the response to hormone treatment in advanced prostate cancer, a study in mice and human prostate cancer cells has found.
Leading UK scientist reveals likely cause of childhood leukaemia
A major new analysis reveals for the first time the likely cause of most cases of childhood leukaemia and that the disease may be preventable.
Researchers discover 40 genes involved in early development of myeloma
Researchers have revealed 40 genes involved in the development of myeloma, increasing our understanding of the complex genetics behind the incurable blood cancer.
Special device facilitates imaging of mice on clinical MRI scanners for neuroblastoma research
A special device for holding mice while they undergo magnetic resonance imaging (MRI) scans on clinical MRI machines – those used on humans – can enhance imaging investigations in mouse models of neuroblastoma, researchers have found.
Scientists uncover a deadly ‘addiction’ in oesophageal cancer
Scientists have discovered a new way of attacking oesophageal cancer cells that could make use of an existing drug in a new approach to treatment.