Under the leadership of Dr Olivia Rossanese, we are seeking to appoint a Team Leader to join The Centre for Cancer Drug Discovery (CCDD) as The Head of Biology and Director of the Centre for Target Validation. Key Requirements The successful candidate must have in-depth knowledge and recent experience in an area of cancer biology relevant to oncology drug discovery. Leadership experience of drug discovery within, or in collaboration with, the pharmaceutical or biotechnology industry as evidenced by publication and/or successful commercial projects. Along with completing the online application form, you will be asked to attach the following documents and failure to do so will mean your application cannot be considered on this occasion: · Full CV · Lists of major publications, achievements, research grants, distinctions. · A PDF of a maximum of five key publications, or other research outputs (e.g. patents) that best demonstrate previous productivity · You must also complete the personal statement section of the application form in the format of a covering letter including the names and contact details of three academic referees Department/Directorate Information: The Division of Cancer Therapeutic's mission is to develop personalised medicines by translating information from the cancer genome and cancer biology into drugs for patient benefit. We implement innovative drug discovery technologies, discover novel mechanism-based drugs, and develop these as rapidly as possible from the laboratory through to hypothesis-testing early clinical trials We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Olivia Rossanese, Email [email protected]

We currently have an exciting opportunity for a self-motivated and experienced HR Adviser to join our HR Operations team. Providing dedicated partnering with client departments, you’ll work closely with line managers to provide proactive and pragmatic advice and guidance on all aspects of people management, taking ownership of a busy employee relations caseload. You will also be responsible for supervising the work of our HR Administrative Team to ensure our monthly payroll input is submitted accurately and on time. You will work closely with other HR teams, including Recruitment, Systems and Information, and Learning and Organisational Development to ensure the provision of an effective, end to end HR service to Scientific and Professional Services teams across the ICR. Key Requirements You will have previous HR advisory experience, as well as a sound experience of managing employee relations cases end-to-end. You’ll need to be highly computer-literate, and have excellent attention to detail, with strong organisational and prioritisation skills to deliver effectively within a fast-paced environment. You will also have first-rate customer service skills to build and maintain collaborative relationships with colleagues across the organisation. Previous line management experience, and of managing small scale team restructures, including knowledge and understanding of TUPE processes would be a distinct advantage. Human Resources Directorate We know that talented, brilliant, passionate people lie at the heart of the ICR. That’s why we provide the policies, procedures, systems and people management infrastructure to recruit, retain, motivate and develop our people to achieve their full potential. We offer both operational and strategic support to teams across the ICR. We are organised across four main functions: HR Operations Learning and Organisational Development Pensions Reward, Information and Systems The ICR’s future success depends on recruiting the very best people with the very best skills and our HR strategy ensures that we have the organisational capacity and capability to deliver this. We encourage all applicants to access the job description pack attached for more detailed information regarding this role. For an informal discussion regarding the Sutton based role, please contact Karen Grieff via email on [email protected].

Under the leadership of Prof. Jessica Downs, we are seeking to a highly motivated individual to join the Epigenetics and Genome Stability Team as Scientific Officer. The ideal candidate will be responsible for the day-to-day running of the lab, maintain general lab equipment and perform experiments and contribute to ongoing research projects using basic cell and molecular biology approaches, including tissue culture, microscopy, and viability assays. Key Requirements The successful candidate must have strong organisational skills, be able to work collaboratively, take initiative and work precisely with excellent attention to detail and produce reproducible results. Experience with microscopy, genetic engineering, viability assays, PCR, cloning, or protein purification, and coding skills are highly desirable. Epigenetics and Genome StabilityTeam The Epigenetics and Genome Stability Team (thedownslab.org) studies the role of chromatin and epigenetic regulation in maintaining genome stability. The goal of this research is to understand how the packaging and organisation of DNA helps to maintain its integrity and prevent Tumourigenesis. We are also exploring how these insights can help identify new therapeutic approaches. Our team is embedded within the Cancer Biology Division at the ICR’s Chester Beatty Laboratories in Chelsea, London. We have a highly supportive and interactive research environment, and state of the art facilities for cell biology, molecular biology, next-generation sequencing and structural biology. We also closely interact with other divisions at the ICR, including Breast Cancer Research, Radiotherapy and Imaging, and Structural Biology. The great variety of disciplines at the ICR will ensure that the successful candidate will be exposed to fantastic research and seminars from all types of backgrounds. Download the job pack for more detailed information regarding this role. For an informal discussion regarding the role, please contact Professor Jessica Downs via email:[email protected]

As Senior Business Development Associate, you will be required to work as part of the ICR’s Business & Innovation Office, to support a portfolio of academics by protecting and commercialising their research, supporting them in securing translational funding and providing support to researchers in their efforts to collaborate with industry partners. You will promote projects to potential ‘customers’ who could be industrial partners, industrial sponsors or venture capitalists, and support colleagues in producing marketing materials as appropriate. The role will include drafting, reviewing, negotiating and agreeing a range of commercial contracts including collaboration agreements and licensing agreements, working within agreed financial and legal frameworks, ensuring obligations to external funders are met and closing deals with Line Manager’s approval. Key Requirements The successful candidate must have: A first degree in a discipline relevant to the ICR's broad research scope (including bioscience, biomedical engineering, physical sciences). A higher degree (Ph.D., MBA or equivalent) is also required. A demonstrated developing understanding and knowledge of commercial contracts, intellectual property management and exploitation. Significant experience of working at the industry:academia interface. Experience in business development, technology transfer or project management. Well-developed analytic and problem-solving skills, ability to interpret contract terms and to advise on their impact appropriately. Good interpersonal skills at all levels; ability to negotiate and influence effectively. Excellent communication skills, both written and verbal, with the ability to present arguments in a clear and concise way. Meticulous attention to detail. Excellent organizational skills with a demonstrated ability to multi-task, prioritize tasks effectively and manage workloads. Understanding of the medtech and biopharma industries. Direct practical experience of drafting, negotiating and closing deals with external partners. Directorate Information The ICR’s Business and Innovation Office (BIO) is vital in meeting our goals for impact. It is our aim as an organisation to change the lives of people with cancer. We are committed to working across academia, government and industry to ensure our findings have benefits for society and the economy, and to grow our funding for research so we can achieve even more in the future. We have ambitions to grow our impact even further over the next period to maximise the chances that our findings will change the lives of patients. This part of our strategy has three goals: • Amplify our research impact • Strengthen our partnerships • Increase commercial income for our research Our approach to KE – and the licensing of intellectual property for our research – is guided by our aim to realise benefits for people with cancer as rapidly as possible and to ultimately defeat cancer. See the ICR webpages on Industry Partnerships for more information: https://www.icr.ac.uk/industry-partnerships We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Ceri Mathews via Email to [email protected]