Cancer discovery news
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Blocking energy production could help treat lung cancer where chemotherapy has limited effect
Targeting an enzyme that helps cells to generate energy could trigger cell death and be a way to treat some forms of lung cancer, even where the effect of chemotherapy is limited.
Prostate cancer DNA test identifies men with six-fold increased risk
A major new study of more than 140,000 men has identified 63 new genetic variations in the DNA code that increase the risk of prostate cancer.
The ICR responds to decision by NICE not to recommend abiraterone as first-line treatment for advanced prostate cancer
The Institute of Cancer Research, London, has expressed disappointment that the prostate cancer drug abiraterone (brand name Zytiga) will not be made available to men with advanced prostate cancer as a first-line treatment on the NHS.
Stunting cell ‘antennae’ could make cancer drugs work again
Scientists have uncovered a completely new way to make cancers sensitive to treatment – by targeting antenna-like structures on cells.
ASCO 2018: Major trial is first to show benefits of immunotherapy in some men with prostate cancer
A major clinical trial has become the first to show benefits of immunotherapy in prostate cancer – for some men with advanced, otherwise untreatable disease.
Acclaimed opera singers come together to support the ICR
A world-class group of opera singers united at the intimate setting of Spencer House this week to celebrate and support the ICR.
Leading UK scientist reveals likely cause of childhood leukaemia
A major new analysis reveals for the first time the likely cause of most cases of childhood leukaemia and that the disease may be preventable.
Study picks out children with incurable brain cancer who could benefit from adult therapy
Children with incurable brain tumours could benefit from potentially life-extending treatment if genetic testing was used to personalise therapy as it is in many adults, major new research reports.
Scientists identify cause of resistance to breakthrough breast and ovarian cancer drug
The study findings could help predict which patients will develop resistance to PARP inhibitors and allow doctors to alter treatment at the earliest possible opportunity.
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Major study gives vital new understandings of how cells divide
The ground-breaking research used mathematical models and pain-staking experiments to clarify the role of a key phase of cell division.
Targeting chemotherapy with genetic testing provides effective treatment for women with aggressive breast cancer
Women with an aggressive form of breast cancer who have faults in their BRCA genes do much better on chemotherapy drug carboplatin than standard treatment, a major clinical trial reports.
Researchers find five sub-types of the brain cancer glioma
The findings come from the largest ever genetic study its kind on glioma and could help us understand the biological mechanisms that trigger the disease.