Science Talk

With our Science Talk blog, we hope to lift the lid on the black box that is the ICR: to show you inside our labs, to introduce you to a few of the people here who make the discoveries, and to allow them to tell some of the stories behind the science. We try to put our discoveries in a wider scientific context, and give an idea of how our science is actually done. We also give you the view from the ICR of important developments in the wider world of cancer research.

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Gynaecological Cancer Awareness Month: New trial offers hope for patients with rare hard-to-treat gynaecological cancer

30/09/20 - Molly Andrews

Around 21,000 people are diagnosed with a gynaecological cancer in the UK each year. This September - Gynaecological Cancer Awareness Month - our Communications Administrator Molly Andrews spoke to Professor Chris Lord and Dr Susana Banerjee about an important new trial in the gynaecological cancer field.
Kaposi sarcoma by Yale Rosen
I think therefore I am – how perception influences sarcoma survivors’ journeys

28/09/20 - Joanne Duffy

Delays in cancer diagnosis can have a profound impact on patients, but so too can their perception of the process. New ICR research shows that there is a complex relationship between patient wellbeing and waiting times. Science Communications Officer Joanne Duffy delves in.
Aoife and her Shetland pony, Bubbles
The little girl driving change: how Aoife’s legacy will help other children

01/09/20 - Clara May

After Aoife Flanagan died of germ cell cancer at the age of three, her mum, Eilish, set up a charity in her daughter’s name to change the future for other children with cancer.
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Supporting our students in these extraordinary times

27/08/20 - Dr Barbara Pittam

Our Registrar and Director of Academic Services, Dr Barbara Pittam, discusses how we are supporting our students as they navigate the impact of Covid-19 pandemic.
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“We don’t know how much time we’ve got left together” – Sally’s melanoma story

17/08/20 - Sally Steadman-South

Scientists at The Institute of Cancer Research have helped discover and develop many targeted treatments that are enabling cancer patients to live longer and with a better quality of life. Sally Steadman-South explains what these research advances have meant for her and her family, and why she needs this work to continue.
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Cancer and COVID-19: how coronavirus has delayed vital cancer treatments

06/07/20 - Henry French

Henry French looks at how an Institute of Cancer Research-led study into the impact of the COVID-19 pandemic on people with cancer helped to start a national debate.
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Can we target cancer’s metabolism by combining new drugs with a fat-free diet?

19/06/20 - Diana Cano Bordajandi

The ICR’s Dr George Poulogiannis and his team have revealed a metabolic weakness in cancer that could be targeted by combining new drugs with a diet free of omega-6 fats. Our Media Officer Diana Cano Bordajandi explains the research findings and their potential implications.
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Men’s Health Week: How our researchers are transforming prostate cancer treatment

15/06/20 - Diana Cano Bordajandi

Professor Nick James, Chief Investigator of the STAMPEDE trial, joined the ICR in December 2019 and is one of our newest Team Leaders. Diana Cano Bordajandi met him to find out more about his current research and future plans, which will help us answer key questions on how to treat men with prostate cancer.
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ASCO 2020: Cancer researchers get together at a distance

29/05/20 - Sarah Wells

At a time when cancer researchers usually descend on Chicago for the biggest cancer conference of the year, Sarah Wells looks ahead at some of the highlights that researchers from The Institute of Cancer Research will be presenting at this year’s virtual edition of the ASCO Annual Meeting.
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Cryo-electron microscopy – the coolest tech in the cancer toolkit

19/05/20 - Graham Shaw

Cryo-electron microscopy is an exciting technology that could revolutionise drug design by seeing complex molecules in unprecedented detail. The Institute of Cancer Research has been at the vanguard in applying it to cancer – and now a new collaboration called the London Consortium for Cryo-EM (LonCEM) is using this super-cooled technique to learn more about the mechanisms of life and cancer.
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How we’re adapting a novel antibody technology to combat COVID-19

04/05/20 - Henry French

Henry French introduces a new project at the ICR, where cancer researchers are turning their expertise in the creation of high-affinity antibodies to new approaches to COVID-19 testing and treatment.
Scanning electron micrograph of a single prostate cancer cell
Prostate Cancer Awareness Month 2020: Immunotherapy, state-of-the-art radiotherapy, olaparib and PSA screening

24/03/20 - Dave Morgan

March is Prostate Cancer Awareness Month. Web Editor Dave Morgan reviews four recent news stories covering different types of prostate cancer research taking place at The Institute of Cancer Research.
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Will I see them graduate? One patient’s perspective on life with advanced breast cancer

22/03/20 - Maureen Kenny

Maureen is 56 and is living with advanced, incurable breast cancer. Before the outbreak of coronavirus, she wrote a blog post about why she’s making the most of the life she has now. This is a very difficult time for many, but here at the ICR we’re doing everything we can to ensure our life-saving work continues, so that we can give people like Maureen more time to spend with their loved ones.
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Living with Lynch syndrome: Cara’s story

22/03/20 - Cara Hoofe

Research carried out by The Institute of Cancer Research, London, into cancer susceptibility genes has transformed our understanding of the inheritance of cancer risk. Genetic information can be used to help people with cancer and their families by informing them about their risk and guiding decisions over personalised cancer treatment. Cara Hoofe was diagnosed with bowel cancer in 2016. She has the inherited condition Lynch syndrome which means she had an 80% chance of developing bowel cancer and has a higher risk of developing womb and ovarian cancer. Here she explains how living with Lynch syndrome has changed her life.
Patient advocate Rob Lester and dog
“My treatment has given me a new lease of life” – Rob’s prostate cancer story

19/03/20 - Rob Lester

Hundreds of thousands of men with prostate cancer across the world are now able to live longer and with a better quality of life, thanks to abiraterone. Discovered and developed by The Institute of Cancer Research, the drug was the first treatment shown to be effective in patients with advanced prostate cancer. Rob Lester is one of those patients, and has been on abiraterone for around 8 years.
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Weighing in on breast cancer risk – considering the effect of weight gain before the menopause

13/03/20 - Joanne Duffy

Obesity is known to be linked to cancer risk, but new research shows that weight gain is linked to a *lower* risk of breast cancer among women before the menopause. In this blog post, Joanne Duffy takes a closer look at the findings and explains how this contributes to our understanding of breast cancer risk factors.
Rhabdomyosarcoma cells (photo courtesy of Dr Ewa Aladowicz in Professor Janet Shipley's team at the ICR)
Small numbers, big impact: the unique challenges of studying rare cancers

07/03/20 - Sarah Wells

New results from an ICR-led clinical trial are set to change the outlook for patients with a rare form of kidney cancer. Sarah Wells takes a look at some of the main challenges in studying rare cancers, and how the ICR’s researchers are going about making discoveries to improve the outlook for the one in five cancer patients with a rare cancer.
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How genomics is transforming cancer treatment

04/03/20 - Diana Cano Bordajandi

Scientists from The Institute of Cancer Research, London, gathered recently at this year’s Festival of Genomics. Diana Cano Bordajandi, Media Officer at The Institute of Cancer Research, reports on the themes that ran through the conference.
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Ageing, cancer, and evolution – what Darwin’s great theory of life means for two unavoidable aspects of living

12/02/20 - Graham Shaw

To celebrate Darwin Day, The Institute of Cancer Research invited world-leading expert on the biology of ageing, Professor Dame Linda Partridge, to talk about how ageing stems from evolutionary processes, and what it means for diseases like cancer.
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International Day of Women and Girls in Science 2020

11/02/20

To celebrate International Day of Women and Girls in Science this year, we're sharing some advice from our scientists about pursuing a career in research.