Translational Sarcoma, Melanoma and Rare Tumour Surgery Group

Mr Myles Smith's group aims to translate basic science innovations generated at the ICR to advance the surgical treatment of cancer – for example, evaluating molecular markers to aid the definition of cancer at the time of surgery.


Our group aims to help the translation of imaging technologies developed at The Institute of Cancer Research to the clinic and bedside.

Tumour-specific preoperative and intraoperative imaging with targeted molecular probes holds great promise in cancer surgery. Improved ability to define the distribution of cancer at the time of surgery would better help define the extent and adequacy of resection, while minimising excision of healthy tissue.

Other benefits include intraoperative staging and the guidance of adjuvant treatments. Successful application of intraoperative targeted molecular imaging to cancer surgery has the potential to translate into improved local control and survival, while reducing the impact of curative interventions. We aim to help the translation of imaging technologies developed at The Institute of Cancer Research to the clinic and bedside.

Myles Smith

Honorary Faculty:

Translational Sarcoma, Melanoma and Rare Tumour Surgery Mr Myles Smith

Myles Smith is a Surgical Oncologist specialising in the surgery of soft tissue sarcomas, malignant melanoma and other rare tumours. He is the Royal College of Surgeons Surgical Tutor and Educational Lead in Surgery at The Royal Marsden NHS Foundation Trust.

Recent discoveries from this group

Artificial intelligence graphic - shows plan view of brain with one hemisphere representing computer circuitry

23/01/25

Scientists have successfully used a form of artificial intelligence (AI) to develop a new imaging approach that makes it easier for radiologists to assess the extent of bone disease in people with advanced prostate cancer or multiple myeloma.
Elekta Unity low to high table positions

21/01/25

Scientists have successfully used real-time MRI to demonstrate that swallowing causes minimal motion of the larynx, known as the voice box, in people undergoing a radiotherapy session for cancer in this part of the body.
Blue man van offering free health checks to men

16/11/24

Mobile testing ‘Man Van’ can diagnose prostate cancer in at-risk groups earlier and more affordably than GPs, according to new research.
An image-guided radiotherapy (IGRT) machine.

30/10/24

Cancer Research UK (CRUK) has awarded The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust a substantial £5.14 million through its radiation research network (RadNet) to support pioneering research in radiation therapy.