Clinical trials methodology research at ICR-CTSU
Our applied methodology research portfolio investigates best practice in trial design, conduct, analysis and reporting.
We specialise in applied methodology research which allows exploration and delivery of complex trials applicable in the real-world to benefit people affected by cancer and improve the quality of future oncology research, while also assessing innovative methodology approaches.
Areas of interest
- biomarker-rich trials and trial platforms
- biological endpoints
- technical radiotherapy studies
- imaging biomarkers
- patient reported outcomes
- use of routine data
- equality, diversity and inclusion
- efficient early phase adaptive designs
- integration of omics and clinical data
Key projects and studies
The DEFINE study: Guidance for Early Phase Dose-Finding trials
This project aims to develop guidance on protocol content and reporting of early-phase trials.