Cancer discovery news
Our researchers are making the discoveries that defeat cancer. Read the latest findings from our world-leading research.
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Statement about NICE draft guidance on enzalutamide
ICR CEO Professor Paul Workman comments on today’s rejection of enzalutamide for advanced prostate cancer before chemotherapy in draft guidance from NICE.
Mutations disrupting a growth-controlling enzyme implicated in a new childhood overgrowth condition
Scientists have shown that mutations in three genes can alter the function of an important growth-controlling enzyme and cause increased growth and intellectual disability in children
Drug combination controls breast cancer for over twice as long
A new drug delays the progression of advanced breast cancer by over twice as long when used in combination with standard treatment, compared to standard treatment alone, a major clinical trial shows.
Statement about rejection of olaparib by NICE
ICR CEO Professor Paul Workman comments on the decision by NICE to reject olaparib for women with BRCA mutated ovarian cancer.
Sleeping cancer cells can ‘wake up’ after decades
Scientists at the ICR have found genetic evidence that cancer cells can go to sleep – avoiding the effects of treatment – only to ‘wake up’ many years later.
Scientists identify key to preventing secondary cancers
Existing class of drugs for osteoporosis could stop the spread of the breast cancer to the bones, the most common site for the disease to spread.
World first as viral immunotherapy for skin cancer shows patient benefit in Phase III trial
A genetically engineered herpes virus can halt the progression of skin cancer by killing cancer cells and sparking the immune system into action against tumours, a landmark clinical trial has shown.
Scientists unveil prostate cancer’s ‘Rosetta Stone’
Landmark study hails new era of personalised treatment for cancers that have spread round the body
Combining targeted cancer drugs is best when used to the max
Combining drugs that inhibit two signalling pathways critical to cancer growth could boost treatment outcomes for some types of cancer, but only when used together at maximum doses, a new study has found.
UK-US study compares radiotherapy with proton therapy in childhood cancer
The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, are leading a collaborative international study looking at the potential benefits of proton radiotherapy for young patients with brain tumours.
Scientists identify a new strategy to kill cancer cells
Scientists have discovered a new strategy to kill cancer cells with defects in genes responsible for DNA repair and cell division.
The ongoing battle with melanoma
Until recently there were no effective treatments for metastatic melanoma, but in the last decade we have seen a flurry of treatment breakthroughs, and scientists at the ICR have been at the heart of the fight against the disease.