Pre-Clinical MRI Group
Professor Simon Robinson’s group focusses on the pre-clinical development and application of non-invasive magnetic resonance imaging (MRI) methods that can be used in the clinic for cancer detection, diagnosis, and monitoring treatment response.
Our group focuses on the application of both established and innovative, quantitative functional MRI techniques to identify case-specific imaging biomarkers in subcutaneous, orthotopic, transgenic and patient-derived xenograft models of cancer.
Located in the Centre for Cancer Imaging, the Robinson laboratory is a multidisciplinary group focussing on the application of both established and innovative, quantitative functional MRI techniques to identify case-specific imaging biomarkers in subcutaneous, orthotopic, transgenic and patient-derived xenograft models of cancer in vivo, thereby establishing their utility to correctly inform on i) the pathology and processes relevant to a particular cancer type, and ii) response/resistance to treatment against these processes.
Exploiting our combined expertise, we have been responsible for the pre-clinical evaluation of numerous functional MRI methods/biomarkers that have been successfully translated and proved informative when translated into aligned clinical imaging investigations of cancer patients. We have also demonstrated how pre-clinical imaging can accelerate the development of promising new treatments, or force early closure of a project which ultimately may not deliver a useful/safe drug.
Professor Simon Robinson
Group Leader:
Pre-Clinical MRI.tmb-propic-md.jpg?Culture=en&sfvrsn=2a433c7a_8 "Simon Robinson square profile (300x300)")
Professor Simon Robinson is applying quantitative functional MRI techniques to evaluate imaging biomarkers of tumour pathophysiology and treatment response in pre-clinical models of cancer.