News and features

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A high magnification image of ovarian clear cell carcinoma (photo: Nephron)
Newly identified biomarker could improve treatment for people with rare type of ovarian cancer

26/03/25

Scientists at The Institute of Cancer Research, London, have identified a gene that affects how ovarian clear cell carcinoma (OCCC) could respond to a new class of drug called ATR inhibitors.
Breast Cancer Cells Credit Min Yu 945x532
Scientists develop new tool to beat cancer’s survival tactics

04/03/25

Scientists have developed a tool which helps them better understand cancer’s survival tactics – and could eventually lead to new treatments for dozens of cancer types.
Human melanoma cells are seen in green escaping from the tumour, with surrounding ECM in purple, arranged perpendicular to the tumour
Scientists discover the ‘roadmap’ that aggressive cancer uses to spread around the body – identifying ways to block its escape

14/02/25

Scientists have discovered a new way to predict which tumours will become aggressive before they metastasise and spread around the body.
Research graph from the endocrine control mechanisms group
New data tool could bring RNA sequencing into standard clinical practice, improving diagnosis and treatment

06/02/25

Researchers have developed a new tool that could help clinicians diagnose the most common type of breast cancer more accurately and make better treatment decisions.
Left: Plates showing the impact of olaparib on BRCA cancer cells and minimal impact of on healthy cells. (Right) Lynparza, olaparib's brand name, drug packaging. Photo credit: Science Museum Group
ICR welcomes NICE recommendation of olaparib for advanced breast cancer

09/01/25

The Institute of Cancer Research, London, strongly welcomes the decision by NICE to recommend that the targeted drug olaparib can be used for locally advanced or metastatic breast cancer.
Breast cancer cell spheroid blue and purple
New understanding of aggressive form of breast cancer paves the way for tests and treatments

10/12/24

Scientists have developed a machine learning tool that can predict how an aggressive type of breast cancer will respond to treatment, and when it will return.
Breast cancer cell
Scientific achievements of 2024

02/12/24

We've selected a range of discoveries from 2023/24 – chosen because they illustrate the quality and breadth of our basic, translational and clinical research and our ambitions under the ICR's research strategy.
Metastatic breast cancer cells in pleural fluid
Powerful new therapy doubles progression-free survival in advanced breast cancer

30/10/24

A three-drug combination for aggressive advanced breast cancer doubles the length of time before the cancer progresses, compared with a drug combination currently available on the NHS, new research has shown.
axel behrens 547x410
Professor Axel Behrens elected as Fellow of the Academy of Medical Sciences

21/05/24

Professor Axel Behrens, Scientific Director of the Cancer Research UK Convergence Science Centre and leader of the Cancer Stem Cell Group at The Institute of Cancer Research, London, has been awarded a prestigious Fellowship by the Academy of Medical Sciences.
Proliferating cells in a tumour organoid of triple-negative breast cancer. Image credit: Dr Rebecca Marlow / ICR
Researchers identify what drives PARP inhibitor resistance in advanced breast cancer

08/05/24

Researchers at The Institute of Cancer Research, London, have increased our understanding of how a cancer drug called a PARP inhibitor stops working in women with breast cancer that has spread. This research could ultimately help predict who’s more likely to respond to these drugs, and could lead to more effective ways to treat the disease.
Breast cancer cells on a black background
Research uncovers how to target ‘sleeping’ breast cancer cells and prevent relapse

26/03/24

Scientists have discovered how breast cancer cells can ‘hibernate’ to avoid treatment and ‘wake up’ years later – causing a relapse that is more difficult to treat.
breast cancer cell
Targeted immunotherapy could lead to pioneering treatment for breast cancer

28/02/24

A new type of immunotherapy that targets non-cancer cells could help prevent the growth and spread of breast cancer tumours, according to new research from the ICR.


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Through our close partnerships with The Royal Marsden and other key UK institutions, we're leading a wide breadth of cancer research across eight divisions and more than 25 research centres and strategic initiatives.