Development and Cancer Group
Dr Amanda Swain’s group is investigating how the molecular processes that form the prostate, gonad and adrenal glands can contribute to tumour formation and progression.
Research, projects and publications in this group
We are studying the molecular and cellular processes that contribute to tumour formation and progression with an aim to provide information that will contribute to improving cancer patient therapy.
Dr Amanda Swain
Group Leader:
Development and Cancer
Dr Amanda Swain is studying how organs such as the prostate, gonads and adrenal gland form normally and the role of these processes in cancer development and progression. As well as running her own research group, Dr Swain is head of the Tumour Profiling Unit.
Researchers in this group
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Dr Amanda Swain's group have written 62 publications
Most recent new publication 11/2024
See all their publicationsWe develop and use a combination of preclinical models to address our functional and therapeutic questions including 3D self organising organoids, patient derived xenografts and genetically modified mouse models.
We have a current focus on three cancers, prostate adenocarcinoma, salivary gland adenoid cystic carcinoma and adrenal cortical carcinoma.
Recent discoveries from this group
Cancer cells pretend to be ‘super fit’ to outsmart normal cells and invade the body
Scientists have discovered that some cancer cells pretend to be ‘super fit’ to fool normal healthy cells into giving them their nutrients, allowing them to expand and spread around the body.
Key driver of aggressive prostate cancer found
A key driver for aggressive forms of prostate cancer has been uncovered by scientists at The Institute of Cancer Research, London.