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Journal Articles

Creamer, A. Fiego, A.L. Agliano, A. Prados-Martin, L. Høgset, H. Najer, A. Richards, D.A. Wojciechowski, J.P. Foote, J.E. Kim, N. Monahan, A. Tang, J. Shamsabadi, A. Rochet, L.N. Thanasi, I.A. de la Ballina, L.R. Rapley, C.L. Turnock, S. Love, E.A. Bugeon, L. Dallman, M.J. Heeney, M. Kramer-Marek, G. Chudasama, V. Fenaroli, F. Stevens, M.M. (2024). Modular Synthesis of Semiconducting Graft Copolymers to Achieve "Clickable" Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting. Adv mater, Vol.36 (20), p. e2300413.  show abstract  full text

Sharma, G. Braga, M.C. Da Pieve, C. Szopa, W. Starzetz, T. Plate, K.H. Kaspera, W. Kramer-Marek, G. (2023). Immuno-PET Imaging of Tumour PD-L1 Expression in Glioblastoma. Cancers (basel), Vol.15 (12).  show abstract  full text

Privitera, L. Waterhouse, D.J. Preziosi, A. Paraboschi, I. Ogunlade, O. Da Pieve, C. Barisa, M. Ogunbiyi, O. Weitsman, G. Hutchinson, J.C. Cross, K. Biassoni, L. Stoyanov, D. Sebire, N. Beard, P. De Coppi, P. Kramer-Marek, G. Anderson, J. Giuliani, S. (2023). Shortwave Infrared Imaging Enables High-Contrast Fluorescence-Guided Surgery in Neuroblastoma. Cancer res, Vol.83 (12), pp. 2077-2089.  show abstract  full text

van Leeuwen, F.W. Schottelius, M. Mottaghy, F.M. Hyafil, F. Lubberink, M. Kramer-Marek, G. Oyen, W.J. (2022). Perspectives on translational molecular imaging and therapy: an overview of key questions to be addressed. Ejnmmi res, Vol.12 (1), p. 31.  full text

Da Pieve, C. Costa Braga, M. Turton, D.R. Valla, F.A. Cakmak, P. Plate, K.-. Kramer-Marek, G. (2022). New Fully Automated Preparation of High Apparent Molar Activity 68Ga-FAPI-46 on a Trasis AiO Platform. Molecules, Vol.27 (3).  show abstract  full text

Mączyńska, J. Raes, F. Da Pieve, C. Turnock, S. Boult, J.K. Hoebart, J. Niedbala, M. Robinson, S.P. Harrington, K.J. Kaspera, W. Kramer-Marek, G. (2022). Triggering anti-GBM immune response with EGFR-mediated photoimmunotherapy. Bmc med, Vol.20 (1), p. 16.  show abstract  full text

Niedbała, M. Malarz, K. Sharma, G. Kramer-Marek, G. Kaspera, W. (2022). Glioblastoma: Pitfalls and Opportunities of Immunotherapeutic Combinations. Onco targets ther, Vol.15, pp. 437-468.  show abstract

Paraboschi, I. Turnock, S. Kramer-Marek, G. Musleh, L. Barisa, M. Anderson, J. Giuliani, S. (2021). Near-InfraRed PhotoImmunoTherapy (NIR-PIT) for the local control of solid cancers: Challenges and potentials for human applications. Crit rev oncol hematol, Vol.161, p. 103325.  show abstract  full text

Paraboschi, I. Privitera, L. Kramer-Marek, G. Anderson, J. Giuliani, S. (2021). Novel Treatments and Technologies Applied to the Cure of Neuroblastoma. Children (basel), Vol.8 (6).  show abstract

Lampis, A. Hahne, J.C. Gasparini, P. Cascione, L. Hedayat, S. Vlachogiannis, G. Murgia, C. Fontana, E. Edwards, J. Horgan, P.G. Terracciano, L. Sansom, O.J. Martins, C.D. Kramer-Marek, G. Croce, C.M. Braconi, C. Fassan, M. Valeri, N. (2021). MIR21-induced loss of junctional adhesion molecule A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer. Cell death differ, Vol.28 (10), pp. 2970-2982.  show abstract  full text

Kastelik-Hryniewiecka, A. Jewula, P. Bakalorz, K. Kramer-Marek, G. Kuźnik, N. (2021). Targeted PET/MRI Imaging Super Probes: A Critical Review of Opportunities and Challenges. Int j nanomedicine, Vol.16, pp. 8465-8483.  show abstract  full text

Turnock, S. Turton, D.R. Martins, C.D. Chesler, L. Wilson, T.C. Gouverneur, V. Smith, G. Kramer-Marek, G. (2020). 18F-meta-fluorobenzylguanidine (18F-mFBG) to monitor changes in norepinephrine transporter expression in response to therapeutic intervention in neuroblastoma models. Sci rep, Vol.10 (1), p. 20918.  show abstract  full text

Mączyńska, J. Da Pieve, C. Burley, T.A. Raes, F. Shah, A. Saczko, J. Harrington, K.J. Kramer-Marek, G. (2020). Immunomodulatory activity of IR700-labelled affibody targeting HER2. Cell death dis, Vol.11 (10), p. 886.  show abstract  full text

Da Pieve, C. Makarem, A. Turnock, S. Maczynska, J. Smith, G. Kramer-Marek, G. (2020). Thiol-Reactive PODS-Bearing Bifunctional Chelators for the Development of EGFR-Targeting [18F]AlF-Affibody Conjugates. Molecules, Vol.25 (7).  show abstract  full text

Burley, T.A. Da Pieve, C. Martins, C.D. Ciobota, D.M. Allott, L. Oyen, W.J. Harrington, K.J. Smith, G. Kramer-Marek, G. (2019). Affibody-Based PET Imaging to Guide EGFR-Targeted Cancer Therapy in Head and Neck Squamous Cell Cancer Models. J nucl med, Vol.60 (3), pp. 353-361.  show abstract  full text

Stowe, C.L. Burley, T.A. Allan, H. Vinci, M. Kramer-Marek, G. Ciobota, D.M. Parkinson, G.N. Southworth, T.L. Agliardi, G. Hotblack, A. Lythgoe, M.F. Branchini, B.R. Kalber, T.L. Anderson, J.C. Pule, M.A. (2019). Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin. Elife, Vol.8.  show abstract  full text

Burley, T.A. Mączyńska, J. Shah, A. Szopa, W. Harrington, K.J. Boult, J.K. Mrozek-Wilczkiewicz, A. Vinci, M. Bamber, J.C. Kaspera, W. Kramer-Marek, G. (2018). Near-infrared photoimmunotherapy targeting EGFR-Shedding new light on glioblastoma treatment. Int j cancer, Vol.142 (11), pp. 2363-2374.  show abstract  full text

Martins, C.D. Kramer-Marek, G. Oyen, W.J. (2018). Radioimmunotherapy for delivery of cytotoxic radioisotopes: current status and challenges. Expert opin drug deliv, Vol.15 (2), pp. 185-196.  show abstract  full text

Martins, C.D. Da Pieve, C. Burley, T.A. Smith, R. Ciobota, D.M. Allott, L. Harrington, K.J. Oyen, W.J. Smith, G. Kramer-Marek, G. (2018). HER3-Mediated Resistance to Hsp90 Inhibition Detected in Breast Cancer Xenografts by Affibody-Based PET Imaging. Clin cancer res, Vol.24 (8), pp. 1853-1865.  show abstract  full text

King, A. Doepner, A. Turton, D. Ciobota, D.M. Da Pieve, C. Wong Te Fong, A.-. Kramer-Marek, G. Chung, Y.-. Smith, G. (2018). Radiosynthesis of the anticancer nucleoside analogue Trifluridine using an automated 18F-trifluoromethylation procedure. Org biomol chem, Vol.16 (16), pp. 2986-2996.  show abstract  full text

Baker, L.C. Sikka, A. Price, J.M. Boult, J.K. Lepicard, E.Y. Box, G. Jamin, Y. Spinks, T.J. Kramer-Marek, G. Leach, M.O. Eccles, S.A. Box, C. Robinson, S.P. (2018). Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma. Front oncol, Vol.8, p. 271.  show abstract  full text

Allott, L. Da Pieve, C. Meyers, J. Spinks, T. Ciobota, D.M. Kramer-Marek, G. Smith, G. (2017). Evaluation of DFO-HOPO as an octadentate chelator for zirconium-89. Chem commun (camb), Vol.53 (61), pp. 8529-8532.  show abstract  full text

Szopa, W. Burley, T.A. Kramer-Marek, G. Kaspera, W. (2017). Diagnostic and Therapeutic Biomarkers in Glioblastoma: Current Status and Future Perspectives. Biomed res int, Vol.2017, p. 8013575.  show abstract  full text

Mansfield, D.C. Kyula, J.N. Rosenfelder, N. Chao-Chu, J. Kramer-Marek, G. Khan, A.A. Roulstone, V. McLaughlin, M. Melcher, A.A. Vile, R.G. Pandha, H.S. Khoo, V. Harrington, K.J. (2016). Oncolytic vaccinia virus as a vector for therapeutic sodium iodide symporter gene therapy in prostate cancer. Gene ther, Vol.23 (4), pp. 357-368.  show abstract  full text

Kramer-Marek, G. Oyen, W.J. (2016). Targeting the Human Epidermal Growth Factor Receptors with Immuno-PET: Imaging Biomarkers from Bench to Bedside. J nucl med, Vol.57 (7), pp. 996-1001.  full text

Denis-Bacelar, A.M. Cronin, S.E. Da Pieve, C. Paul, R.L. Eccles, S.A. Spinks, T.J. Box, C. Hall, A. Sosabowski, J.K. Kramer-Marek, G. Flux, G.D. (2016). Pre-clinical quantitative imaging and mouse-specific dosimetry for 111In-labelled radiotracers. Ejnmmi res, Vol.6 (1), p. 85.  show abstract  full text

Da Pieve, C. Allott, L. Martins, C.D. Vardon, A. Ciobota, D.M. Kramer-Marek, G. Smith, G. (2016). Efficient [(18)F]AlF Radiolabeling of ZHER3:8698 Affibody Molecule for Imaging of HER3 Positive Tumors. Bioconjug chem, Vol.27 (8), pp. 1839-1849.  show abstract  full text

Xu, Z. Bagci, U. Mansoor, A. Kramer-Marek, G. Luna, B. Kubler, A. Dey, B. Foster, B. Papadakis, G.Z. Camp, J.V. Jonsson, C.B. Bishai, W.R. Jain, S. Udupa, J.K. Mollura, D.J. (2015). Computer-aided pulmonary image analysis in small animal models. Med phys, Vol.42 (7), pp. 3896-3910.  show abstract  full text

Adesina, S.K. Holly, A. Kramer-Marek, G. Capala, J. Akala, E.O. (2014). Polylactide-based paclitaxel-loaded nanoparticles fabricated by dispersion polymerization: characterization, evaluation in cancer cell lines, and preliminary biodistribution studies. J pharm sci, Vol.103 (8), pp. 2546-2555.  show abstract  full text

Mohd Nafi, S.N. Generali, D. Kramer-Marek, G. Gijsen, M. Strina, C. Cappelletti, M. Andreis, D. Haider, S. Li, J.-. Bridges, E. Capala, J. Ioannis, R. Harris, A.L. Kong, A. (2014). Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer. Oncotarget, Vol.5 (15), pp. 5934-5949.  show abstract

Nafi, S. Generali, D. Kramer-Marek, G. Gijsen, M. Strina, C. Cappelletti, M. Andreis, D. Haider, S. Li, J.L. Bridges, E. Capala, J. Ioannis, R. Harris, A.L. Kong, A. (2014). Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer. Oncotarget, .  show abstract

Feldinger, K. Generali, D. Kramer-Marek, G. Gijsen, M. Ng, T.B. Wong, J.H. Strina, C. Cappelletti, M. Andreis, D. Li, J.-. Bridges, E. Turley, H. Leek, R. Roxanis, I. Capala, J. Murphy, G. Harris, A.L. Kong, A. (2014). ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer. Oncotarget, Vol.5 (16), pp. 6633-6646.  show abstract

Kramer-Marek, G. Gore, J. Korc, M. (2013). Molecular imaging in pancreatic cancer--a roadmap for therapeutic decisions. Cancer lett, Vol.341 (2), pp. 132-138.  show abstract

Bagci, U. Kramer-Marek, G. Mollura, D.J. (2013). Automated computer quantification of breast cancer in small-animal models using PET-guided MR image co-segmentation. Ejnmmi res, Vol.3 (1), p. 49.  show abstract

Capala, J. Kong, A. Kramer-Marek, G. Gijsen, M. (2012). Reply. J nucl med, .

Kramer-Marek, G. Gijsen, M. Kiesewetter, D.O. Bennett, R. Roxanis, I. Zielinski, R. Kong, A. Capala, J. (2012). Potential of PET to predict the response to trastuzumab treatment in an ErbB2-positive human xenograft tumor model. J nucl med, Vol.53 (4), pp. 629-637.  show abstract

Kramer-Marek, G. Bernardo, M. Kiesewetter, D.O. Bagci, U. Kuban, M. Aras, O. Zielinski, R. Seidel, J. Choyke, P. Capala, J. (2012). PET of HER2-positive pulmonary metastases with 18F-ZHER2:342 affibody in a murine model of breast cancer: comparison with 18F-FDG. J nucl med, Vol.53 (6), pp. 939-946.  show abstract

Kramer-Marek, G. Capala, J. (2012). The role of nuclear medicine in modern therapy of cancer. Tumor biology, Vol.33 (3), pp. 629-640.

Mitsunaga, M. Nakajima, T. Sano, K. Kramer-Marek, G. Choyke, P.L. Kobayashi, H. (2012). Immediate in vivo target-specific cancer cell death after near infrared photoimmunotherapy. Bmc cancer, Vol.12, p. 345.  show abstract

Kramer-Marek, G. Longmire, M.R. Choyke, P.L. Kobayashi, H. (2012). Recent Advances in Optical Cancer Imaging of EGF Receptors. Current medicinal chemistry, Vol.19 (28), pp. 4759-4766.  full text

Jagoda, E.M. Lang, L. Bhadrasetty, V. Histed, S. Williams, M. Kramer-Marek, G. Mena, E. Rosenblum, L. Marik, J. Tinianow, J.N. Merchant, M. Szajek, L. Paik, C. Cecchi, F. Raffensperger, K. Jose-Dizon, J.-. Bottaro, D.P. Choyke, P. (2012). Immuno-PET of the hepatocyte growth factor receptor Met using the 1-armed antibody onartuzumab. J nucl med, Vol.53 (10), pp. 1592-1600.  show abstract

Kramer-Marek, G. Capala, J. (2012). Can PET imaging facilitate optimization of cancer therapies?. Curr pharm des, Vol.18 (18), pp. 2657-2669.  show abstract

Dahl, M. Bouchelouche, P. Kramer-Marek, G. Capala, J. Nordling, J. Bouchelouche, K. (2011). Sarcosine induces increase in HER2/neu expression in androgen-dependent prostate cancer cells. Molecular biology reports, Vol.38 (7), pp. 4237-4243.  full text

Kramer-Marek, G. Shenoy, N. Seidel, J. Griffiths, G.L. Choyke, P. Capala, J. (2011). 68Ga-DOTA-affibody molecule for in vivo assessment of HER2/neu expression with PET. Eur j nucl med mol imaging, Vol.38 (11), pp. 1967-1976.  show abstract  full text

Gijsen, M. Kramer-Marek, G. Bennett, R. Harris, A. Capala, J. Kong, A. (2011). Trastuzumab treatment induces ADAM17 and HER ligands in vivo. Cancer research, Vol.71.

Kramer-Marek, G. Shenoy, N. Seidel, J. Griffiths, G. Choyke, P. Capala, J. (2011). Ga-68-radiolabeled DOTA-affibody molecule for in vivo assessment of HER2 expression with PET. Cancer research, Vol.71.

Jagoda, E. Bhadrasetty, V. Lixin, L. Williams, M. Histed, S. Gabriela, K.-. Marik, J. Tinianow, J. Merchant, M. Szajek, L. Paik, C. Bottaro, D. Choyke, P. (2011). Comparison of [Zr-89] and [Br-76] labeled MetMAb, a one-armed monoclonal antibody targeting the Met receptor tyrosine kinase (Met), in human gastric carcinoma (MKN-45) and glioblastoma (U87 MG) cells and xenografts. Journal of labelled compounds & radiopharmaceuticals, Vol.54, pp. S172-S172.

Lyakhov, I. Kuban, M. Zielinski, R. Kramer-Marek, G. Capala, J. (2010). HER2-and EGFR-specific Affiprobes - Novel recombinant optical probes for cell imaging. Cancer research, Vol.70.

Lyakhov, I. Zielinski, R. Kuban, M. Kramer-Marek, G. Fisher, R. Chertov, O. Bindu, L. Capala, J. (2010). HER2- and EGFR-specific affiprobes: novel recombinant optical probes for cell imaging. Chembiochem, Vol.11 (3), pp. 345-350.  show abstract  full text

Watson, R.P. Kramer-Marek, G. Capala, J. (2010). Instrumental neutron activation analysis of gold in mouse tissues. Abstracts of papers of the american chemical society, Vol.240.

Morgan, N.Y. Kramer-Marek, G. Smith, P.D. Camphausen, K. Capala, J. (2009). Nanoscintillator conjugates as photodynamic therapy-based radiosensitizers: calculation of required physical parameters. Radiat res, Vol.171 (2), pp. 236-244.  show abstract  full text

Nawalany, K. Rusin, A. Kepczyński, M. Mikhailov, A. Kramer-Marek, G. Snietura, M. Połtowicz, J. Krawczyk, Z. Nowakowska, M. (2009). Comparison of photodynamic efficacy of tetraarylporphyrin pegylated or encapsulated in liposomes: in vitro studies. J photochem photobiol b, Vol.97 (1), pp. 8-17.  show abstract

Kramer-Marek, G. Kiesewetter, D.O. Capala, J. (2009). Changes in HER2 expression in breast cancer xenografts after therapy can be quantified using PET and (18)F-labeled affibody molecules. J nucl med, Vol.50 (7), pp. 1131-1139.  show abstract

Zielinski, R. Lyakhov, I. Jacobs, A. Chertov, O. Kramer-Marek, G. Francella, N. Stephen, A. Fisher, R. Blumenthal, R. Capala, J. (2009). Affitoxin--a novel recombinant, HER2-specific, anticancer agent for targeted therapy of HER2-positive tumors. J immunother, Vol.32 (8), pp. 817-825.  show abstract  full text

Capala, J. Kramer-Marek, G. Lee, S.B. Hassan, M. Kiesewetter, D.O. Puri, A. Chernomordik, V. Gandjbakhche, A. Griffiths, G. Blumenthal, R. (2009). Molecular targeting of HER2 for diagnosis and therapy of breast cancer. Cancer research, Vol.69 (2), pp. 349S-349S.

Watson, R. Popelka-Filcoff, R. Kramer-Marek, G. Mackey, E.A. Spatz, R.O. Capala, J. (2009). ANYL 96-Quantitation of gold in biological tissues using neutron activation analysis. Abstracts of papers of the american chemical society, Vol.238.

Kramer-Marek, G. Kiesewetter, D.O. Martiniova, L. Jagoda, E. Lee, S.B. Capala, J. (2008). [18F]FBEM-Z(HER2:342)-Affibody molecule-a new molecular tracer for in vivo monitoring of HER2 expression by positron emission tomography. Eur j nucl med mol imaging, Vol.35 (5), pp. 1008-1018.  show abstract

Kiesewetter, D.O. Krämer-Marek, G. Ma, Y. Capala, J. (2008). Radiolabeling of HER2 specific Affibody(R) molecule with F-18. J fluor chem, Vol.129 (9), pp. 799-805.  show abstract  full text

Lee, S.B. Hassan, M. Fisher, R. Chertov, O. Chernomordik, V. Kramer-Marek, G. Gandjbakhche, A. Capala, J. (2008). Affibody molecules for in vivo characterization of HER2-positive tumors by near-infrared imaging. Clin cancer res, Vol.14 (12), pp. 3840-3849.  show abstract  full text

Puri, A. Kramer-Marek, G. Campbell-Massa, R. Yavlovich, A. Tele, S.C. Lee, S.-. Clogston, J.D. Patri, A.K. Blumenthal, R. Capala, J. (2008). HER2-Specific Affibody-Conjugated Thermosensitive Liposomes (Affisomes) for Improved Delivery of Anticancer Agents. Journal of liposome research, Vol.18 (4), pp. 293-307.  full text

Kramer-Marek, G. Kiesewetter, D.O. Martiniova, L. Rodriguez, Y. Capala, J. (2007). F-18-Z(HER2)-Affibody: A new tracer for molecular imaging of HER2-expressing tumors by PET. Molecular cancer therapeutics, Vol.6 (12), pp. 3478S-3478S.


Conferences

Dar, D.Rodak, M.Da Pieve, C.Gorczewska, I.Sharma, G.Chmielik, E.Niedbala, M.Bzowski, P.d'Amico, A.Bobek-Billewicz, B.Nowicka, E.Tarnawski, R.Kaspera, W.Kramer-Marek, G. (2024). Imaging PD-L1 in the brain-Journey from the lab to the clinic., England. Neuro Oncol, .


Patents and patent applications

Kramer-Marek, Radiolabeled Affibody® Molecules.US 8,303,960 B2.