We are studying the molecular and cellular processes that contribute to tumour formation and progression with an aim to provide information that will contribute to improving cancer patient therapy. 

We develop and use a combination of preclinical models to address our functional and therapeutic questions including 3D self organising organoids, patient derived xenografts and genetically modified mouse models.

We have a current focus on three cancers, prostate adenocarcinoma, salivary gland adenoid cystic carcinoma and adrenal cortical carcinoma.