Research overview

Dr Alicia Okines, Breast Cancer Systemic Therapeutic Trials group

My research focuses on clinical trials in metastatic breast cancer and I have a particular interest in central nervous system diseases which have arisen from advanced breast cancers.

I am currently leading the ROLo trial evaluating pre-clnical findings from Professor Chris Lord’s laboratory in a clinical trial of a ROS1 targeted agent in lobular breast cancer and diffuse gastric cancer. This study is funded by Breast Cancer Now and Pfizer.

I will lead the PAveMenT trial of palbociclib and avelumab in advanced AR positive triple negative breast cancer, evaluating pre-clinical findings from Professor Nick Turner’s laboratory in a phase 1b study. The study is funded by a Breast cancer Now Catalyst Grant.