Antibody Facility
The Antibody Facility, established by the Centre for Genome Stability at the Institute of Cancer Research, is dedicated to developing high-quality single-chain variable fragment (scFv) antibodies. Our goal is to empower cutting-edge research by providing researchers with highly specific and cost-effective antibody solutions.
Method and capability
We use a human naïve scFv phage display library with a diversity of 6.37×10¹⁰, sourced from 458 donors across 5 ethnic groups, maximizing diversity for the rapid generation of monoclonal antibodies with high specificity for your target protein. This powerful technology enables the screening of extensive antibody libraries, ensuring that only the best candidates with optimal binding properties are selected for your research.
Single-chain variable Fragments (scFvs) in research
Single-chain variable fragments (ScFvs) are smaller antibody fragments composed of variable heavy (VH) and variable light (VL) domains connected by a short linker. They retain the antigen-binding specificity of full-length antibodies while offering several advantages in research applications. Their compact size allows better tissue penetration, making them ideal for imaging and hard to reach targets. They are cost-effective, stable, and can be easily modified for diverse applications.
Contact us
To discuss your ideas or projects, please get in touch:
Dr. Divya Duscharla
Antibody Facility Manager
Email: [email protected]
Feedback and oversight
This facility is overseen by Tina Daviter, Head of Core Research Facilities and the Centre for Genome Stability Steering Group, ICR.