Careers at the ICR
We provide exceptional opportunities for the best scientists, clinicians, and professional and administrative staff, and excellent academic and recreational facilities at our two London sites, in Chelsea and Sutton.
As a world-leading research organisation, The Institute of Cancer Research, London, offers a fantastic working environment, great opportunities for career development and the chance to make a real difference for cancer patients. We aim to recruit and develop the best – with positions for outstanding scientists and clinicians, and the most talented professional or administrative staff.
Different types of positions at the ICR
Our aim is to attract the best people in cancer research. We offer an excellent working environment, competitive salaries and good staff benefits. There is a range of career paths at the ICR, in scientific research, research support, and professional and administrative positions.
We offer a variety of professional and administrative roles in areas such as facilities, fundraising, communication, IT, human resources, research services and education and library services.
Our professional services teams are tailored to meet the needs of a research organisation, and many of our employees in these teams have backgrounds in science, or experience of working with scientists and clinicians.
Our specialist finance team is experienced at dealing with research grants, and staff within our Business and Innovation Office have the expertise to negotiate complex collaborative agreements between the ICR and pharmaceutical and biotech companies.
We're recruiting the top figures in cancer research to work in a vibrant and confident culture that consistently produces world-changing research.
To become part of our career faculty, you will be an established senior researcher and have the proven leadership skills and international research credibility to direct major scientific programmes, and build and manage a motivated and high-performing scientific team.
Our culture emphasises the importance of collaborative working to address the big challenges in cancer research, and you will be expected to form part of the wider ICR team. You will also recruit and develop the research leaders of the future.
To join the ICR you’ll be a talented scientist looking for the next step after your initial postdoctoral studies. You’ll be ready to start leading a team independently under the mentorship of a leading senior scientist.
Personal fellowships, funded by a variety of medical research agencies and charities, are the usual route for new leaders to join us in areas in which we are traditionally very strong, such as cancer biology. Success as a fellow will put you on a fast-track route to gaining a long-term career at the ICR.
To join us you will have, or be in the process of gaining, a personal fellowship from one of the major national or international funding bodies, such as the Wellcome Trust, Cancer Research UK, one of the Research Councils, the Royal Society or the National Institute for Health Research.
For PhD graduates looking for a postdoctoral role. We offer a competitive salary, rigorous training, many opportunities for professional development, and an open and inclusive working culture.
We offer clinicians a variety of working opportunities, from working as a postdoctoral researcher in one of our eight scientific divisions, to carrying out independent research as a clinician scientist or clinical research fellow, to heading a specialised research team. We also offer clinicians the opportunity to develop their specialty, through a variety of taught or research-based postgraduate degrees.
Collaboration between scientists and clinicians is essential for the translational nature of the cutting-edge research carried out at the ICR. It gets new treatments to patients more quickly, and allows our researchers to learn from experience in the clinic.
Moving to the UK
We attract staff from all over the world. Find all the information you need to move to the United Kingdom to work with us.
Staff benefits
Find out more about the staff benefits we offer, including a competitive salary package, annual leave entitlements, and sports and social facilities.Some of our current vacancies
Postdoctoral Training Fellow
Under the leadership of Claudio Alfieri, we are seeking to appoint a Postdoctoral Training Fellow to join the Molecular Mechanisms of Cell Cycle Regulation Group at the Chester Beatty Laboratories, Fulham Road in London. This project aims to investigate the molecular mechanisms of cell cycle regulation by macromolecular complexes involved in cell proliferation decisions, by combining genome engineering, proteomics and in situ structural biology. For general information on Post Doc's at The ICR can be found here. Key Requirements The successful candidate must have a PhD in cellular biochemistry and experience in Cryo-EM and CLEM is desirable. The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 7 years Department/Directorate Information: The candidate will work in the Molecular Mechanisms of Cell Cycle Regulation Group within the ICR Division of Structural Biology headed by Prof. Laurence Pearl and Prof. Sebastian Guettler. The division has state-of-the-art facilities for protein expression and biophysics/x-ray crystallography, in particular the Electron Microscopy Facility is equipped with a Glacios 200kV with Falcon 4i detector with Selectris energy filter and the ICR has access to Krios microscopes via eBIC and the LonCEM consortium. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Claudio Alfieri via Email on [email protected]
Higher Scientific Officer - Drug Discovery Biology, Centre for Protein Degradation
We are seeking to recruit a Higher Scientific Officer within the Induced Proximity Therapeutics (IPT) Team in the ICR Centre for Protein Degradation to support our molecular glue and PROTAC drug discovery projects and expand induced proximity technology. The IPT team focuses on three main areas of research: Cancer target validation Screening, profiling and molecular mechanism of action of molecular glue and PROTAC degraders Novel E3 ligase biology and ligand discovery The successful candidate will work in a multidisciplinary team and play a key role in target validation, developing in vitro and cell-based assays, and pharmacological characterisation of novel molecular glue degraders and PROTACs, but may also contribute to other activities. About you The successful candidate: Will be a strong team player who is technically minded and passionate about science and cancer drug discovery Will hold a first degree, and preferably a PhD, in biological science or biochemistry Will have experience in cancer biology/target validation, genetic manipulation techniques, in vitro and cell-based assay development and pharmacological compound profiling Experience in targeted protein degradation will be a significant advantage. Department/Directorate Information This position will be based in the ICR's Centre for Protein Degradation, a part of the Centre for Cancer Drug Discovery (CCDD) specialising in developing novel drug modalities that re-wire tumour cells' signalling by targeted degradation of key oncogenic drivers. Our experienced biologists work closely with medicinal chemists, biophysicists, computational scientists, oncology specialists and physicians on discovering new medicines - molecular glue degraders and PROTACs - using innovative screening platforms and characterising their mechanisms of action, as well as expanding the repertoire of novel degradable drug targets and E3 ligases (enzymes that mediate protein degradation). Our research provides a nucleus for the academics and pharmaceutical industry to explore therapeutic potential of targeted protein degradation from laboratory hypothesis-testing to early clinical trials, for the benefit of cancer patients. What we offer A dynamic and supportive research environment in one of the successful academic cancer drug discovery centres in the UK Access to state-of-the-art facilities and professional development Collaboration with leading drug discovery and oncology scientist Competitive salary and pension To learn more about this role, please download the attached job pack. For informal inquiries, please contact Dr Agnieszka Konopacka, Group Leader, Induced Proximity Therapeutics, Centre for Protein Degradation via email: [email protected].
Programme Manager
We are looking to appoint an experienced and committed Clinical Trial Programme Manager to work within the Drug Development Unit (DDU) at the ICR and RM. The Unit delivers industry/academic -sponsored early phase clinical trials of new anticancer drugs. The DDU is one of the leading clinical trial units in the world that undertakes early-phase oncology trials for solid tumours. Over the years, DDU has played a significant role in transitioning several anti-cancer drugs from bench -to-bedside, many of which have now become standard of care cancer treatments. The Unit has a dedicated ward within the Royal Marsden Hospital for the development of novel cancer therapeutics, which we believe will improve the care of cancer patients. Key Requirements The post holder will be educated to at least degree level in life sciences or a health related area, with previous experience of managing and working in clinical trials with an excellent understanding of the conduct of Phase I oncology trials. They must be able to manage a team of skilled people and several complex studies at a time. The post holder will be key to the communication and operations with the unit’s management group, clinical study team and with external partners, ensuring that studies are run to protocol and in accordance with ICH-GCP. The post holder must be highly organised and able to plan work around a busy clinical unit. They should have excellent communication and interpersonal skills in order to interact effectively with unit staff and patients. Institution Information The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment. The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer. The Royal Marsden NHS Foundation Trust is a world-leading specialist cancer hospital. The Institute of Cancer Research works in close partnership with The Royal Marsden to take the results of our research rapidly into the clinic, with the aim of developing better treatments for cancer patients. Department/Directorate Information The ICR and The Royal Marsden are internationally renowned for our work together to conduct early- and late-phase clinical trials. Our joint Drug Development Unit, which sees around 300 patients per year, is one of the largest centres for phase I trials in the world and makes an important contribution to the worldwide effort to discover and develop new cancer drugs. The Drug Development Unit, is led by Professor Johann de Bono, comprises of clinicians, scientists, data and study management staff, and focuses on providing a seamless conduit between pre-clinical drug discovery, proof of principle Phase-1 clinical trials and tumour specific evaluation of novel agents. The Unit undertakes both industry-sponsored and investigator-initiated trials of new anti-cancer drugs. The Unit is rapidly expanding and provides an excellent opportunity for the post holder to develop a variety of skillsets. This post also benefits from generous annual leave entitlement and a pension. To apply for this post, please submit an online application including a supporting statement, detailing reasons why you are applying for the post and with your CV. We encourage all applicants to access the job pack attached for more detailed information regarding this role. Due to the high volumes of applications we receive, we reserve the right to close the advert before the published closing date once we have received a sufficient number of applications. Therefore we advise that you to submit your application, as early as possible to avoid disappointment.
Learning and Organisational Development Programme Coordinator
About the Role We are seeking a Learning and Development Programme Coordinator to join our department and contribute to all aspects of the scheduling, delivery and evaluation of the ICR’s training offer for staff and students and supporting the implementation of our new learning management system. The successful candidate will play a key role in liaising with internal and external trainers to coordinate our annual programme of training and events, managing training budgets, producing training reports and evaluations and project managing the move to a new learning management system. Key Responsibilities Project managing the implementation of a new learning management system (LMS) Training programme management and scheduling Liaising with internal and external training providers Evaluating the annual training programme Managing the resource bank of on demand training About You We are looking for a self-motivated individual who is highly organised and can work to tight deadlines. The ideal candidate will have a Degree level qualification in Business, Communication, HR or equivalent experience. Proven experience in managing the delivery of a structured programme of events. Significant experience of implementing LearnUpon or other Learning Management System. Excellent organizational and time-management skills. Good commercial awareness and experience of dealing directly with suppliers. Strong communication and interpersonal abilities. Proficiency in Microsoft Office, Learn Upon/other LMS. What We Offer A supportive and collaborative working environment. Opportunities for professional development and career progression. Competitive salary and pension Department/Directorate Information The Learning and Organisation Team are part of the HR Directorate and provide a wide range of training and career development support for all staff and students covering: research skills, management and leadership development and personal development. We also lead on supporting equality and diversity including external awards such as Athena SWAN and HR Excellence in Research. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact [email protected].
Postdoctoral Training Fellow - Medicinal Chemistry
Under the guidance of Dr Gurdip Bhalay, we are looking for a talented synthetic chemist with an interest in medicinal chemistry to join a project team focussing on the design and application of small molecules in immuno-oncology, which seeks to harness the body’s own immune system to destroy cancer cells. Our aim is to use multi-parameter optimisation in conjunction with structure-based drug design to generate high quality pre-clinical candidate drugs. About you The successful candidate will work as part of a multidisciplinary project team to use in house data and structural information to design new molecules then develop and execute synthetic routes to make these compounds in the lab. The candidate will develop their existing skills in organic chemistry as well as their knowledge and experience of applied medicinal chemistry. Candidates who are nearing completion of their PhD may apply, but confirmation on awarded PhD is required within 6 months of employment. The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 7 years. For general information on Postdocs at The ICR, more information can be found here. Department/Directorate Information The Cancer Research UK Cancer Therapeutics Unit, within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 200 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our world-class biologists, chemists and drug metabolism specialists work together focusing on new molecular targets emerging from human genome and ground breaking cell biology research. This is an exciting and fast moving area of cancer research, and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment. Department/Directorate Information: Medicinal Chemistry Team 1 is one of several medicinal chemistry teams based on our Sutton site, in state-of-the-art laboratories, in the Centre for Cancer Drug Discovery. What we offer A dynamic and supportive research environment Access to state-of-the-art facilities and professional development opportunities Collaboration with leading researchers in the field Competitive salary and pension We encourage all applicants to access the job pack attached for more detailed information regarding this role. Due to the high volumes of applications we receive, we reserve the right to close the advert before the published closing date once we have received a sufficient number of applications. Therefore we advise that you to submit your application, as early as possible to avoid disappointment.
Higher Scientific Officer - Biology, Target Validation and Genome Stability Group
Under the guidance of Prof Joanna Loizou, we are seeking to recruit a Higher Scientific Officer to join the Target Validation and Genome Stability group within the Centre for Target Validation to carry out lab-based cell biology research focused on potential therapeutic targets in cancer. About you The successful candidate must have: At least a Masters level qualification in Cell Biology or an aligned subject (PhD in Cell Biology or an aligned subject is desirable) Knowledge of cancer biology Knowledge of experimental approaches to therapeutic target validation in cancer Skills in cell biology techniques used for target validation Expertise in a range of biology readouts used for screening and biomarker detection Experience working in lab-based cell biology (can include PhD) Department/Directorate Information The Target Validation and Genome Stability Group, led by Prof Joanna Loizou, focuses on identifying vulnerabilities in the DNA damage response to generate pre-clinical information that can lead to the identification of novel targets for drug discovery programmes. The ICR has established a Centre for Target Validation that will accelerate the translation of ICR and collaborator research into drug discovery programmes. The Centre will deliver bespoke, hypothesis-driven data packages to support decision-making for launch of drug discovery projects. The Centre’s dedicated resources, including biology, functional genomics, assay sciences, chemistry, and bioinformatics teams, will support joint project teams that combine the deep biological and therapeutic knowledge of ICR investigators with the validation and technical expertise of drug discovery scientists. Scientists in the Centre for Target Validation will work closely with colleagues in the ICR’s Centre for Protein Degradation to exploit emerging technology and protein degradation tools for robust target validation experiments. The Centre for Target Validation will serve as a hub, connecting researchers to expertise and resources that will validate and streamline robust, targets into drug discovery programmes in the ICR’s Centre for Cancer Drug Discovery or into collaborative programmes with external commercial therapy discovery partners. What we offer A dynamic and supportive research environment Access to state-of-the-art facilities and professional development opportunities Collaboration with leading researchers in the field Competitive salary and pension We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Prof Joanna Loizou via Email on [email protected].
Trustee
Join Our Board as a Trustee The Institute of Cancer Research is seeking 2 passionate and committed individuals to join our Board of Trustees. As a trustee, you will play a vital role in shaping the strategic direction of our organisation, ensuring effective governance, and making a meaningful impact in our community. About Us The ICR is one of the most influential cancer research institutes with an outstanding track record of achievement dating back more than 100 years. Our mission is to make the discoveries that defeat cancer through world-leading research and excellent learning and teaching. Who We're Looking For We are seeking to recruit 2 Trustees, each with one of the following skill-sets: A Trustee who is a Senior Clinical Scientist/Academic or Researcher in Industry with substantive leadership experience A Trustee with the background and experience to advise the ICR on policy and public affairs matters Role & Responsibilities Provide strategic guidance and oversight. Ensure financial sustainability and compliance. Support the leadership team in achieving the organisation's goals. Advocate for the organisation and its mission. Time Commitment The Board of Trustees meets in person four times a year. In addition, there are occasional online Board Briefings. Trustees are also encouraged if available to attend some fundraising and other events such as the annual Carol Service and the October Degree Ceremony. In addition we expect our Trustees (where available) to serve on one of our Board sub-committees. We welcome applications from candidates with protected characteristics. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact the Secretariat at [email protected]. Join us and help make a difference!
Higher or Senior Scientific Officer
Under the guidance of Prof Trevor Graham, we are seeking to recruit a Higher or Senior Scientific Officer to To study epigenome evolution in colorectal cancer The successful candidate will play a key role in The principal duty of the post will be to undertake research into the evolutionary dynamics that underpin colorectal cancer development and response to treatment. The post holder will lead experimental lab work to generate and analyse molecular genomics data, especially single cell data, from patient material and other sample types. About you The successful candidate must have: PhD in molecular biology or other relevant area. Ability to perform advanced NGS experiments for the analysis of cancer genomes Ability to conduct single cell/nuclei dissociation, sorting and NGS analysis in cell lines and/or patient biopsies Proven expertise in advanced NGS technologies, including RNA-seq, DNA-seq, and single-cell sequencing. Hands-on experience with single-cell technologies such as scRNA-seq, scATAC-seq, or spatial transcriptomics. Good communication skills and the ability to interact effectively with other team members. Department/Directorate Information The Centre for Evolution and Cancer (CEC), within the Division of Cancer Biology, is a multidisciplinary centre, comprising around 50 staff dedicated to understanding cancer evolution and leveraging this knowledge for translational benefit. Our interests span early detection through to treatment of metastatic disease. The CEC brings together expertise in evolutionary theory, computational biology and bioinformatics together with cutting-edge research ability in cell and molecular biology to provide a stimulating and creative interdisciplinary environment where new approaches to tackling cancer can thrive. The Genomics and Evolutionary Dynamics team combine molecular and cellular biology together with mathematical and computational modelling to study the evolution of malignancy. We focus on early detection in the gastrointestinal tract, colorectal cancer evolution and treatment response, and pan-cancer genomics. We perform basic research into the biology of the human body in health and disease and translate our findings to improve clinical care of patients affected by cancer. What we offer A dynamic and supportive research environment Access to state-of-the-art facilities and professional development opportunities Collaboration with leading researchers in the field Competitive salary and pension We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Prof Trevor Graham [email protected].