The purpose of the National Study of Colorectal Cancer Genetics is to collect information from individuals who have been diagnosed with colorectal cancer who also have a family history of the condition, so that we can try and identify new hereditary factors (genes) that may lead to the development of colorectal cancer and further increase our understanding of why this condition develops and perhaps provide new targets for chemotherapy.

Study Type: 

Observational Study    

REC no: MREC/02/0/97
Disease: Colon; Rectum
Design Type: Genetic Epidemiology

Closure Date: 30/09/2018
Sample Size: 30,000 patients
Inclusion Criteria: Patients aged 18-59 at date of diagnosis, who have had a diagnosis of adenocarcinoma of the colon or rectum (large bowel) within the last five years. Appendix and Anal cancer is not included in the study. Patients must have a family history (defined as a parent, sibling or child also diagnosed with colorectal cancer) 

Control recruitment has now closed.

Chief Investigator: Professor Richard Houlston  

Current Progress

The study as of 31 March 2016 has recruited 26,032 patients.

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