Careers at the ICR
We provide exceptional opportunities for the best scientists, clinicians, and professional and administrative staff, and excellent academic and recreational facilities at our two London sites, in Chelsea and Sutton.
As a world-leading research organisation, The Institute of Cancer Research, London, offers a fantastic working environment, great opportunities for career development and the chance to make a real difference for cancer patients. We aim to recruit and develop the best – with positions for outstanding scientists and clinicians, and the most talented professional or administrative staff.
Different types of positions at the ICR
Our aim is to attract the best people in cancer research. We offer an excellent working environment, competitive salaries and good staff benefits. There is a range of career paths at the ICR, in scientific research, research support, and professional and administrative positions.
We offer a variety of professional and administrative roles in areas such as facilities, fundraising, communication, IT, human resources, research services and education and library services.
Our professional services teams are tailored to meet the needs of a research organisation, and many of our employees in these teams have backgrounds in science, or experience of working with scientists and clinicians.
Our specialist finance team is experienced at dealing with research grants, and staff within our Business and Innovation Office have the expertise to negotiate complex collaborative agreements between the ICR and pharmaceutical and biotech companies.
We're recruiting the top figures in cancer research to work in a vibrant and confident culture that consistently produces world-changing research.
To become part of our career faculty, you will be an established senior researcher and have the proven leadership skills and international research credibility to direct major scientific programmes, and build and manage a motivated and high-performing scientific team.
Our culture emphasises the importance of collaborative working to address the big challenges in cancer research, and you will be expected to form part of the wider ICR team. You will also recruit and develop the research leaders of the future.
To join the ICR you’ll be a talented scientist looking for the next step after your initial postdoctoral studies. You’ll be ready to start leading a team independently under the mentorship of a leading senior scientist.
Personal fellowships, funded by a variety of medical research agencies and charities, are the usual route for new leaders to join us in areas in which we are traditionally very strong, such as cancer biology. Success as a fellow will put you on a fast-track route to gaining a long-term career at the ICR.
To join us you will have, or be in the process of gaining, a personal fellowship from one of the major national or international funding bodies, such as the Wellcome Trust, Cancer Research UK, one of the Research Councils, the Royal Society or the National Institute for Health Research.
For PhD graduates looking for a postdoctoral role. We offer a competitive salary, rigorous training, many opportunities for professional development, and an open and inclusive working culture.
We offer clinicians a variety of working opportunities, from working as a postdoctoral researcher in one of our eight scientific divisions, to carrying out independent research as a clinician scientist or clinical research fellow, to heading a specialised research team. We also offer clinicians the opportunity to develop their specialty, through a variety of taught or research-based postgraduate degrees.
Collaboration between scientists and clinicians is essential for the translational nature of the cutting-edge research carried out at the ICR. It gets new treatments to patients more quickly, and allows our researchers to learn from experience in the clinic.
Moving to the UK
We attract staff from all over the world. Find all the information you need to move to the United Kingdom to work with us.
Staff benefits
Find out more about the staff benefits we offer, including a competitive salary package, annual leave entitlements, and sports and social facilities.Some of our current vacancies
Postdoctoral Training Fellow
Under the leadership of Claudio Alfieri, we are seeking to appoint a Postdoctoral Training Fellow to join the Molecular Mechanisms of Cell Cycle Regulation Group at the Chester Beatty Laboratories, Fulham Road in London. This project aims to investigate the molecular mechanisms of cell cycle regulation by macromolecular complexes involved in cell proliferation decisions, by combining genome engineering, proteomics and in situ structural biology. For general information on Post Doc's at The ICR can be found here. Key Requirements The successful candidate must have a PhD in cellular biochemistry and experience in Cryo-EM and CLEM is desirable. The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 10 years Department/Directorate Information: The candidate will work in the Molecular Mechanisms of Cell Cycle Regulation Group within the ICR Division of Structural Biology headed by Prof. Laurence Pearl and Prof. Sebastian Guettler. The division has state-of-the-art facilities for protein expression and biophysics/x-ray crystallography, in particular the Electron Microscopy Facility is equipped with a Glacios 200kV with Falcon 4i detector with Selectris energy filter and the ICR has access to Krios microscopes via eBIC and the LonCEM consortium. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Claudio Alfieri via Email on [email protected]
Postdoctoral Training Fellow
Under the guidance of Prof. Simon Robinson, we are seeking to recruit a Postdoctoral Training Fellow to develop and apply pre-clinical MRI techniques to characterise the tumour microenvironment and its response to treatment in vivo. The successful candidate will play a key role in exploiting MRI for adaptive radiotherapy, performing MRI-embedded investigations of tumour response to radiotherapy/immunotherapy drug combinations. About you The successful candidate must have a PhD (or supervisor’s pre-approval) in Physical or Biomedical Science, and accomplished in the application of imaging techniques for the investigation of cancer. Experience in the development & application of MRI protocols, ideally in a pre-clinical setting, MRI image acquisition and associated software programming for data analysis would be advantageous. The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as a PTDF at the ICR ( this includes experience gained at PDTF level prior to joining the ICR). Department/Directorate Information The position will be based within the Centre for Cancer Imaging, part of the Division of Radiotherapy & Imaging at the Institute of Cancer Research. What we offer A dynamic and supportive research environment Access to state-of-the-art facilities and professional development opportunities Collaboration with leading researchers in the field Competitive salary and pension We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Prof. Robinson via email ([email protected]).
Group Leader ICR Clinical Trials and Statistics Unit
Under the leadership of Professor Emma Hall, we are seeking to appoint a Research Group Leader to join The CRUK Clinical Trials and Statistics Unit at the ICR. The ICR-CTSU is a research-led, academic trials unit established in the 1980s. The main objective of the ICR-CTSU is to lead the design, conduct and analysis of multi-centre national and international randomised controlled clinical trials of cancer treatments which will directly influence routine clinical practice within the NHS and worldwide. Key Requirements The successful candidate will ideally have: Higher Degree (MSc or PhD) in Medical Statistics or an allied subject. Significant experience as a biostatistician with a research interest in clinical trials methodology. Broad understanding of cancer research Evidence of intellectual leadership (Career Faculty) Ability to generate research funds to support the group. As part of your online application, you will be required to upload your full CV which will pre-populate your application form, you will also be asked to attach the following documents and failure to do so will mean your application cannot be considered on this occasion: Lists of major publications, achievements, research grants and distinctions. Research plan (five to six pages outlining your current research interests and research programme for the next 5 years). The Research plan would be expected to align to ICR-CTSU objectives and include a focus on a methodological area of research which could be applied to the design or analysis of cancer trials. A PDF of a maximum of five key publications, or other research outputs (e.g. patents) that best demonstrate previous productivity or a single document giving hyperlinks to these outputs. You must also complete the personal statement section of the application form in the format of a cover letter including the names and contact details of three academic referees Department/Directorate Information: Division of Clinical Studies Clinical Trials and Statistics Unit (ICR-CTSU) The ICR-CTSU is a Cancer Research UK-funded, internationally recognised methodologist led clinical trials unit, providing cancer-focused clinical trial research expertise. We lead pioneering, efficient, high-quality, and impactful trials across the phases. Our expertise ranges from experimental medicine early phase studies exploring biological efficacy to trials which may deliver widespread change to routine practice, underpinned by applied methodology to drive forward clinical trial innovation. See our clinical trials Joining as a group leader, you will be given outstanding support to help you to continue to develop in your career. Along with a start-up package of funding, you will also have access to resources to establish your group, including support for recruiting key group members, such as PhD students and postdoctoral researchers. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Professor Emma Hall ([email protected])
Head of Business Development – Academic Research and Services Contracts
About the Role We are seeking a Head of Business Development – Academic Research and Services Contracts to join the Business and Innovation directorate to manage and lead the Academic Research and Services Contracts team and contribute to the ICR’s objectives through the provision of a professional and efficient contracts service. This is a job share with 0.6FTE the other job share is already in post. The successful candidate will play a key role in taking responsibility (either directly or through their business team) for the drafting, review and negotiation of non-income bearing contracts such as CDAs, MTAs and academic collaboration agreements across all 8 research Divisions within ICR; for academic consulting; the commercialisation of reagents and services, the negotiation of grant funder terms and conditions; and the promotion of translational funding opportunities. Key Responsibilities These involve leading the Academic Research and Services Contracts team including line-managing, motivating and developing staff members and ensuring satisfactory performance. Prioritising and allocating workloads within the Academic Research and Services Contracts Team to ensure timely completion of the work allocated to the team and delivery of an effective service. Contributing to the development and maintenance of management information systems for contracts and other Business and Innovation Office information; the preparation of management reports, metrics and other management information for ICR, working with other staff and delegating tasks as necessary. Liaising regularly with the Heads of Divisions (or their deputies) and other senior colleagues to understand their needs and priorities About You The successful candidate will have a science degree qualification in a discipline relevant to the ICR and/or a PhD in a relevant subject (or equivalent experience). Excellent knowledge of contract law and strong analytical and problem-solving skills, with the ability to interpret contract terms and to advise on their impact appropriately. What We Offer A supportive and collaborative working environment. Opportunities for professional development and career progression. Competitive salary and pension We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Jon Wilkinson via Email on [email protected].
Tessa Jowell Brain Cancer Mission: Clinical Fellowship in Neuro Oncology
The Tessa Jowell Fellowship The Tessa Jowell Fellowships, hosted in collaboration with Tessa Jowell Centres of Excellence (TJCE), are designed to support clinicians to address the needs of the future of neuro-oncology. The 12-month funded Fellowships aim to train highly skilled clinicians that are capable of appreciating the breadth of comprehensive brain tumour management and can integrate knowledge and experience in personalizing and optimising cancer care. The intention is for the Fellow to gain experience with the ultimate objective of leading high impact practice changing neuro-oncology clinical trials in the future as a Chief Investigator. This particular fellowship is for a dedicate Neuro-Oncology Clinical Fellow within the Drug Development Unit at the Institute of Cancer Research and The Royal Marsden. The Institute of Cancer Research The ICR is one of the world’s most influential cancer research institutes with an outstanding record of achievement dating back more than 100 years. The scientists at the ICR have contributed to identifying several cancer genes, discovered multiple practice changing cancer drugs and have developed precision therapies. Together with our hospital partner The Royal Marsden (RM) , we are rated in the top four centres for cancer research and treatment worldwide. The ICR was ranked first in the UK for its research in biological sciences in a combined assessment of research quality, impact and environment; and overall, second in the UK among all higher Education institutions in REF 2021 analysis. The Royal Marsden The Royal Marsden is recognised worldwide for the quality of it cancer services. The Trust’s strategic aim is to achieve excellence in cancer treatment and diagnosis, through partnership and collaboration. The prime purpose of the Trust is the provision of state of the art cancer services as well as enabling research into the development of improved methods of prevention, diagnosis and treatment of cancer. Its other main purpose is teaching and the dissemination of knowledge both nationally and internationally. The Drug Development Unit, The DDU within the ICR and Royal Marsden, is a dedicated Clinical Trials Unit, with bespoke facilities to conduct early phase clinical trials. The Unit, led by Professor Johann de Bono, comprises of clinicians, scientists, data and study management staff, and focuses on providing a seamless conduit between pre-clinical drug discovery, proof of principle Phase-1 clinical trials and tumour specific evaluation of novel agents. The Unit undertakes both industry-sponsored and investigator-initiated trials of new anti-cancer drugs. The Unit is rapidly expanding and provides an excellent opportunity for the post holder to develop a variety of skillsets. Summary of Role TJBCM Fellowships are for applicants who are near completion of training in clinical or medical oncology. Applicants will need to be able to demonstrate that they meet the range of skills and experience outlined in the person specification. The fellowship is focused on providing extensive clinical experience working with novel targeted therapies as well as experience in all aspects of Phase 1 trial conduct, over twelve months. Importance is placed on the longitudinal experience of managing brain tumours in these settings, in which clinical oncology trainees usually have approximately 4-months and medical oncology trainees have zero experience within a standard training programme. Fellows are further encouraged to gain experience and understanding of the multi-disciplinary approach to brain tumour management, with the opportunity to spend one day a week observing and learning from the various disciplines involved in brain tumour management. The objective of the Tessa Jowell Drug Development Unit Fellowship is to offer the opportunity for a medical oncology (or clinical oncology) trainee who wishes to gain specific experience in early clinical trials with a specific focus on neuro-oncology. The post provides: extensive clinical experience working with novel targeted therapies in oncology(clinics, ward work and consultant ward rounds) experience in all aspects of Phase 1 trial conduct from protocol development, trial setup, trial conduct in line with GCP, clinical and administrative management of trials, decision making on dose escalation, correlation of clinical and laboratory findings (pharmacokinetics, pharmacodynamics). The majority of the anti-cancer drugs being explored at often at a very early first in human stage and span a breath of immune-oncology, DNA damage-response therapies, targeted therapies as well as novel anti-cancer strategies. Opportunities to be involved in projects leading to publication of manuscripts, and trial presentation at national and international meetings. For suitable candidates, there is the option to develop grant applications and translational project proposals for higher degrees (MD/PhD). To apply for this post, please submit an online application including a supporting statement, detailing reasons why you are applying for the post and include your CV. We encourage all applicants to access the job pack attached for more detailed information regarding this role.
Higher Scientific Officer - Drug Discovery Biology, Centre for Protein Degradation
We are seeking to recruit a Higher Scientific Officer within the Induced Proximity Therapeutics (IPT) Team in the ICR Centre for Protein Degradation to support our molecular glue and PROTAC drug discovery projects and expand induced proximity technology. The IPT team focuses on three main areas of research: Cancer target validation Screening, profiling and molecular mechanism of action of molecular glue and PROTAC degraders Novel E3 ligase biology and ligand discovery The successful candidate will work in a multidisciplinary team and play a key role in target validation, developing in vitro and cell-based assays, and pharmacological characterisation of novel molecular glue degraders and PROTACs, but may also contribute to other activities. About you The successful candidate: Will be a strong team player who is technically minded and passionate about science and cancer drug discovery Will hold a first degree, and preferably a PhD, in biological science or biochemistry Will have experience in cancer biology/target validation, genetic manipulation techniques, in vitro and cell-based assay development and pharmacological compound profiling Experience in targeted protein degradation will be a significant advantage. Department/Directorate Information This position will be based in the ICR's Centre for Protein Degradation, a part of the Centre for Cancer Drug Discovery (CCDD) specialising in developing novel drug modalities that re-wire tumour cells' signalling by targeted degradation of key oncogenic drivers. Our experienced biologists work closely with medicinal chemists, biophysicists, computational scientists, oncology specialists and physicians on discovering new medicines - molecular glue degraders and PROTACs - using innovative screening platforms and characterising their mechanisms of action, as well as expanding the repertoire of novel degradable drug targets and E3 ligases (enzymes that mediate protein degradation). Our research provides a nucleus for the academics and pharmaceutical industry to explore therapeutic potential of targeted protein degradation from laboratory hypothesis-testing to early clinical trials, for the benefit of cancer patients. What we offer A dynamic and supportive research environment in one of the successful academic cancer drug discovery centres in the UK Access to state-of-the-art facilities and professional development Collaboration with leading drug discovery and oncology scientist Competitive salary and pension To learn more about this role, please download the attached job pack. For informal inquiries, please contact Dr Agnieszka Konopacka, Group Leader, Induced Proximity Therapeutics, Centre for Protein Degradation via email: [email protected].
Postdoctoral Training Fellow - Bioinformatics
Professor Johann de Bono’s translational research team is seeking a talented Postdoctoral Training Fellow. The programme focuses on integrating multi-omic and clinical data, including single cell and spatial data as well as hyperplex immunocytochemical data, to help develop novel therapeutic strategies against cancer. For general information on Post Docs at The ICR can be found here. Key Requirements The successful candidate will be highly motivated and possess robust bioinformatic, scientific, and analytical skills, with a proactive approach to learning and applying new techniques, including artificial intelligence. Primary responsibilities will involve working with integrated datasets including clinical trial datasets comprising next-generation sequencing data and other applications relevant to the analysis of DNA and RNA sequencing, as well as protein assays. Familiarity with cancer genomics is desirable. The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as a PTDF at the ICR ( this includes experience gained at PDTF level prior to joining the ICR). Department/Directorate Information: Professor Johann de Bono is a world leader in anticancer drug development, biomarker studies, and prostate cancer care. His team conducts biomarker-driven clinical and translational research to accelerate the development of novel cancer therapies and improve understanding of cancer biology, drug sensitivity and resistance. His team has driven major advances in cancer care through early and late stage trials, and he has led pivotal phase III trials of several prostate cancer drugs including abiraterone, cabazitaxel, enzalutamide, lutetium PSMA and olaparib. His team consists of basic, translational and clinical scientists, and is embedded in a vibrant world-class research environment. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Wei Yuan via email on [email protected] Due to the high volumes of applications that we receive, we reserve the right to close the advert before the published closing date, once we have received a sufficient number of applications. Therefore, we advise that you to submit your application, as early as possible to avoid disappointment.
Human Resources Adviser
We currently have an exciting opportunity for a self-motivated and experienced HR Adviser to join our HR Operations team for 12 months. Providing dedicated partnering with client departments, you’ll work closely with line managers to provide proactive and pragmatic advice and guidance on all aspects of people management, taking ownership of a busy employee relations caseload. You will also be responsible for supervising the work of our HR Administrative Team to ensure our monthly payroll input is submitted accurately and on time. You will work closely with other HR teams, including Recruitment, Systems and Information, and Learning and Organisational Development to ensure the provision of an effective, end to end HR service to Scientific and Professional Services teams across the ICR. Key Requirements You will have previous HR advisory experience, as well as a sound experience of managing employee relations cases end-to-end. You’ll need to be highly computer-literate, and have excellent attention to detail, with strong organisational and prioritisation skills to deliver effectively within a fast-paced environment. You will also have first-rate customer service skills to build and maintain collaborative relationships with colleagues across the organisation. Previous line management experience, and of managing small scale team restructures, including knowledge and understanding of TUPE processes would be a distinct advantage. Human Resources Directorate We know that talented, brilliant, passionate people lie at the heart of the ICR. That’s why we provide the policies, procedures, systems and people management infrastructure to recruit, retain, motivate and develop our people to achieve their full potential. We offer both operational and strategic support to teams across the ICR. We are organised across four main functions: HR Operations Learning and Organisational Development Pensions Reward, Information and Systems The ICR’s future success depends on recruiting the very best people with the very best skills and our HR strategy ensures that we have the organisational capacity and capability to deliver this. We encourage all applicants to access the job description pack attached for more detailed information regarding this role. For an informal discussion regarding the Sutton based role, please contact Karen Grieff via email on [email protected].